POS0993 RADIOLOGICAL CERVICAL INVOLVMENT IN ANKYLOSING SPONDYLITIS

Background Cervical involvement in ankylosing spondylitis (AS) is particularly disabling and has been poorly studied yet. Actual radiologic scoring design to assess disease progression does not provide a comprehensive picture of the cervical AS. [1] Association with clinical features such as psoriasis are discussed. Objectives We aimed radiographic AS clinico-biological parameters associated this specific location. Methods Cross-sectional study based on analysis subgroup patients included French BambooSpine cohort, originally designed genetic risk factors structural severity. The was Parisian hospitals have access images entire spine Picture Archiving Communication System (PACS) shared by all University Hospitals Paris. A double reading performed rheumatologist/radiologist pair until consensus reached, identify syndesmophytes, zygapophyseal joint (ZJ) posterior ligament structures (PLS) at each level, syndesmophytes thoracic region, ZJ PLS lumbar region. Results Of 113 assessed patients, 101 were men, mean age 53 years (+/- 11 years) 27 13 duration (Table 1). those whose HLA B27 status known, 85% (70/82) carriers. Among 86 radiological involvement, 83% had 86% 24% involvement. In (15%) fusion without syndesmophytes. 26/113 completely free any while 30/113 maximal (anterior posterior). univariate analyses, HLA-B27 significantly level (p=0.016). type psoriasis. Low educational (not beyond secondary school) syndesmophytic (p=0.035). There non-significant trend for an association between arthritis Table 1. Clinical Men (n,%) 101/113 89,4% Age diagnosis (mean, SD) 31,2 11,68 Duration evolution 27,0 13,0 Smoking ever 65/112 58,0 % Chronic Back Pain (for > 3 months) 109/113 96,5% Chest pain 45/110 40,9% Buttock 78/109 71,6% Arthritis 36/111 32,4% Enthesitis 38/112 33,9% Dactylitis 6/111 5,4% 70/82 85,4% CRP 87/103 84,5% X ray sacro-iliitis 112/112 100% Personnal history -Uveitis 41/113 36,3% -Inflammatory bowel 13/113 11,5% -Reactive 2/112 1,8% -Psoriasis 19/111 17,1% Conclusion very frequent (76% severe population) but psoriasis, usually thought. Zygapophyseal present cases exclusive 15 cases. This latter form disease, i.e. more difficult diagnose, should be systematically among and/or reduced mobility. References [1]Wanders AJB, Landewé RBM, Spoorenberg A, et al. What most appropriate method spondylitis? & Rheumatism 2004 Disclosure Interests None declared